| Characteristic | Details |
|---|---|
| Active Ingredient | Sildenafil Citrate |
| Available Dosages | 100 mg, 50 mg, 25 mg |
| Form | Tablet |
| Indication | Treats Female Sexual Arousal Disorder (FSAD) |
| Onset of Action | 30 to 60 minutes |
| Duration | Up to 4 hours |
| Learn More About Femalegra | |
Pharmacokinetics
The pharmacokinetics of Femalegra involve absorption, distribution, metabolism, and excretion. After oral administration, sildenafil 100 mg is rapidly absorbed. Peak plasma concentrations occur within 30 to 120 minutes. Food intake delays this absorption. Bioavailability is approximately 41%. Sildenafil binds to plasma proteins, mostly albumin, at a rate of 96%. It undergoes hepatic metabolism, primarily by CYP3A4 and CYP2C9 pathways.
The elimination half-life of sildenafil 100 mg is around 3 to 5 hours. Renal and biliary excretion are the primary routes for metabolites. Plasma clearance is about 41 liters per hour. Femalegra undergoes extensive first-pass metabolism, which reduces systemic bioavailability. The drug is predominantly cleared as metabolites in feces and urine.
How should Femalegra be used?
Femalegra should be used as directed by a healthcare professional. Dosage adjustments are necessary for individual response and tolerance. Typically, sildenafil 100 mg is recommended for optimal efficacy. It should be consumed 30 to 60 minutes before sexual activity. The tablet should be swallowed whole with water.
Avoid taking Femalegra more than once daily. A healthcare provider should be consulted for any dosage changes. Ingestion with high-fat meals can delay onset. Always adhere to prescribed instructions for effective results. Keep an eye on side effects and report any unusual reactions.
Femalegra Contraindications
Femalegra has specific contraindications. Patients with cardiovascular disorders should exercise caution. Use is contraindicated with nitrate medications. Severe hepatic impairment precludes the use of sildenafil 100 mg. Additionally, hypotension or recent stroke history warrants alternative treatment. Hypersensitivity to sildenafil or any excipient in the formulation also contraindicates usage.
Women who are pregnant or breastfeeding should consult their healthcare provider before use. Interactions with other medications can affect efficacy and safety. Proper medical guidance is essential before initiation.
Cautions with other medicines
Femalegra interacts with numerous medications. Concomitant use with nitrates can lead to severe hypotension. CYP3A4 inhibitors like ketoconazole increase sildenafil levels. Protease inhibitors also impact plasma concentration. Dosage adjustment may be necessary.
Antihypertensive drugs can potentiate the blood pressure-lowering effect of Femalegra. Alpha-blockers may cause symptomatic hypotension. Monitoring for adverse effects is crucial when combined with other medications. Consult a healthcare provider for a comprehensive interaction assessment.
Effects of Femalegra
Femalegra primarily enhances blood flow to the pelvic region. This action improves arousal and sexual satisfaction in women. The medication is effective in managing Female Sexual Arousal Disorder (FSAD). Sildenafil 100 mg augments nitric oxide’s effect by inhibiting phosphodiesterase type 5 (PDE5).
Common effects include facial flushing, headache, and nasal congestion. Some women experience dizziness and visual disturbances. Always report severe side effects to a healthcare professional. For more scientific insights, refer to PubMed.
Femalegra Over The counter
Femalegra is available by prescription. Over-the-counter sales are not authorized. A prescription ensures safe usage under medical supervision. Self-medication can lead to adverse outcomes. Dosage needs to be tailored by healthcare providers based on individual health status.
Pharmaceutical supervision is vital for maintaining efficacy and safety. Reliable online platforms offer consultation services. Ensure authenticity and legality when seeking this medication. Femalegra requires careful administration to prevent complications and optimize results.
Data source:
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